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The latest antibodies news from News Medical |
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ADC Internalization Detection Using a pH-Sensitive Dye-Labeled Antibody
To support internalization evaluation of ADCs, ACRO have developed a specialized Antibody Internalization Detection Reagent (Cat. No. IGG-PZF2001), featuring a pH-sensitive dye that labels the human IgG Fc region. The reagent forms a stable fluorescent complex that enables detection of antibody endocytosis within cells. It delivers enhanced fluorescence in acidic compartments with minimal background.
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 | | A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg. | | | | An investigational monoclonal antibody called bentracimab can safely and effectively reverse potentially catastrophic bleeding complications linked to ticagrelor, a common drug used to treat patients with acute coronary syndromes, prior heart attack, stroke, and coronary artery disease. | | | | A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses. | | | | Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukaemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma. | |
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